Pain is a complex and deeply personal experience. It involves both physical sensations and emotional responses, acting as the body’s warning system when something isn’t right. While pain is common in many chronic conditions, it has historically been under-recognised and under-discussed in cystic fibrosis (CF).

Aiden’s story is a powerful example of how Australian research is transforming cystic fibrosis treatment. By participating in the ORIGIN-1 trial, Aiden helped generate the evidence that expanded national access to Trikafta for people with rare CFTR mutations. His journey highlights the life-changing impact of personalised medicine and community-driven research — opening doors for many Australians living with cystic fibrosis.