#About Cystic Fibrosis - Cure4CF Cystic fibrosis (CF) is a life-shortening inherited condition that affects the lungs, digestive system and other vital organs. It causes thick, sticky mucus to build up, making it harder to breathe, absorb nutrients and fight infections. CF is relentless — it requires daily treatments, ongoing hospital care and constant vigilance. While advances in care have improved life expectancy, there is still no cure.